The cannabinoid system and immune modulation

The cannabinoid system and immune modulation.

Studies on the effects of marijuana smoking have evolved into the discovery and description of the endocannabinoid system. To date, this system is composed of two receptors, CB1 and CB2, and endogenous ligands including anandamide, 2-arachidonoyl glycerol, and others. CB1 receptors and ligands are found in the brain as well as immune and other peripheral tissues. Conversely, CB2 receptors and l...

Cholinergic Receptor Sensitivity Following Pharmacological Modulation of the Immune System

Objective. To study the effect of immunomodulators on learning and memory and on cholinergic receptor sensitivity. Methods. Animals were initially treated for a period of 8 days with cyclosporine/levamisole/saline. They were then subjected to passive avoidance training and 48 hrs later, the retention test for the passive avoidance task was conducted. Twenty-four hours after the retention tests ...

Experimental Cannabinoid 2 Receptor-Mediated Immune Modulation in Sepsis

Sepsis is a complex condition that results from a dysregulated immune system in response to a systemic infection. Current treatments lack effectiveness in reducing the incidence and mortality associated with this disease. The endocannabinoid system offers great promise in managing sepsis pathogenesis due to its unique characteristics. The present study explored the effect of modulating the CB2 ...

Nutrition and Immune System

تداوم سلامتی انسان با سیستم ایمنی بدن مرتبط است. این سیستم از بافتهای متنوع، سلولها و عواملی تشکیل شده است که از بدن در مقابل آنتی ژنهای مضر و پاتوژنها حفاظت می کند. سلولهای ایمنی در زمان وجود عفونت جهت محدود کردن ضایعات سلولی و بافتی، تجمع می یابند. یک شبکه نظارت متشکل از سلولهای ایمنی در تشخیص سلولهای غیر طبیعی عمل می کنند. توانایی بدن در محافظت از خود در برابر عوامل خارجی، بخصوص باکتریها، و...

The Mucosal Immune System: Modulation by Microemulsion